Guadecitabine

INN name:	Guadecitabine
Lab codes:	Decitabine deoxyguanosine; Decitabine deoxyguanosine dinucleotide; S-110; SGI-110
Chemical name:	2'-deoxy-5-azacytidylyl-(3'→5')-2'-deoxyguanosine
Molecular formula:	C18H24N9O10P
Chemical Structure:
CAS Registry Number:	929901-49-5
Originator:	SuperGen
Developer:	Astex Pharmaceuticals; Groupe Francophone des Myelodysplasies
Class:	Antineoplastics
Mechanism of Action:	Antimetabolites; DNA cytosine 5 methyltransferase 1 inhibitors
WHO ATC code:	L01B (Antimetabolites)
EPhMRA code:	L1B (Antimetabolites)
Clinical Trials: Conditions Phases Status Leukemia, Myeloid, Acute Phase 3 Recruiting Non-small Cell Lung Cancer Phase 2 Completed MDS Phase 2 Recruiting Hepatocellular Carcinoma Phase 2 Active, not recruiting Previously Treated Metastatic Colorectal Cancer Phase 1 / Phase 2 Recruiting MDS;   CMML;   AML Phase 1 / Phase 2 Active, not recruiting Ovarian Cancer Phase 1 / Phase 2 Active, not recruiting Germ Cell Tumor Phase 1 Recruiting Metastatic Colorectal Cancer Phase 1 Recruiting Acute Myeloid Leukemia Phase 1 Recruiting
Recent activities on the drug: