Abemaciclib

INN name:	abemaciclib
Lab codes:	LY-2835219
Chemical name:	N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-benzimidazol-6-yl]pyrimidin-2-amine
Molecular formula:	C27H32F2N8
Chemical Structure:
CAS Registry Number:	1231929-97-7
Originator:	Eli Lilly
Class:	Antineoplastic
Mechanism of Action:	Cyclin-dependent kinase 4, 6 inhibitors
WHO ATC code:	L01X-E
EPhMRA code:	L1H
Clinical Trials:
Conditions Phases Interventions Status Breast Cancer Phase 3 Combination Recruiting Breast Neoplasms Phase 3 Combination Recruiting Non Small Cell Lung Cancer Phase 3 Combination Recruiting Breast Cancer|Brain Metastases Phase 2 Alone Recruiting Breast Cancer|Hormone Receptor Positive Tumor|Early-Stage Breast Carcinoma Phase 2 Combination Not yet recruiting Mantle Cell Lymphoma Phase 2 Alone Active, not recruiting Metastatic Breast Cancer Phase 2 Alone Active, not recruiting Non-Small Cell Lung Cancer Stage IV Phase 2 Combination Recruiting Advanced Cancer Phase 1 Combination Active, not recruiting Breast Neoplasms Phase 1 Combination Recruiting Carcinoma, Non-small Cell Lung Phase 1 Combination Recruiting Carcinoma, Non-Small-Cell Lung|Neoplasm Metastasis Phase 1 Combination Recruiting Hepatic Insufficiency|Healthy Phase 1 Alone Completed Neoplasm Metastasis|Lymphoma Phase 1 Alone Active, not recruiting Neoplasm|Neoplasm Metastasis Phase 1 Combination Active, not recruiting
Recent activities on the drug: