Emicizumab

INN name:	For more details visit: http://drugspider.com Emicizumab
Chemical name:	Immunoglobulin G4-kappa, bispecific, anti-[Homo sapiens F9a (activated coagulation factor F9, activated coagulation factor IX) and anti-[Homo sapiens F10 (coagulation factor 10, coagulation factor X)], humanized monoclonal antibody; gamma4 heavy chain (1-448) [humanized VH (Homo sapiens IGHV3-23*04 (87.80%) -(IGHD)-IGHJ4*01 (1- 123)), IGHG4*01 (CH1 K100>Q (202) (124-221), hinge S10>P (231) (222-233), CH2 F84.3>Y (299) (234-343), CH3 E12>K (359), R88>K (412), H115>R (438), L125>P (448) (344-448), CHS>del) (124-448)], (137-214')-disulfide with kappa light chain (1’-214’) [humanized V-KAPPA (Homo sapiens IGKV1-39*01 (80.00%) -IGKJ4*01) [6.3.9] (1'-107') -Homo sapiens IGKC*01, Km3 (108'-214')]; gamma4 heavy chain (1-444) [VH (Homo sapiens IGHV1- 2*02 (75.50%) -(IGHD)-IGHJ6*03 Q120>E (111''), T123>L (114'') (1''-119'')), IGHG4*01 (CH1 A100>Q (198'') (120''- 217''), hinge S10>P (227'') (218''-229''), CH2 F84.3>Y (295''), (230''-339''), CH3 R88>K (408), K119>E (438), L125>P (444) (340''-444''), CHS>del) (120''-444'')], (133''- 214''')-disulfide with kappa light chain (1'''-214''') [humanized V-KAPPA (Homo sapiens IGKV1-39*01 (80.00%) -IGKJ4*01) [6.3.9] (1'''-107''') -Homo sapiens IGKC*01, Km3 (108'''-214''')]; dimer (229-225":232-228")- bisdisulfide
Alternate Name:	Immunoglobulin G4-kappa, bispecific, anti-(homo sapiens F9a (activated coagulation factor F9, activated coagulation factor IX) and anti-(homo sapiens F10 (coagulation factor 10, coagulation factor X)), humanized monoclonal antibody Heavy chain anti-F9a QVQLVESGGG LVQPGGSLRL SCAASGFTFS YYDIQWVRQA PGKGLEWVSS 50 ISPSGQSTYY RREVKGRFTI SRDNSKNTLY LQMNSLRAED TAVYYCARRT 100 GREYGGGWYF DYWGQGTLVT VSSASTKGPS VFPLAPCSRS TSESTAALGC 150 LVKDYFPEPV TVSWNSGALT SGVHTFPAVL QSSGLYSLSS VVTVPSSSLG 200 TQTYTCNVDH KPSNTKVDKR VESKYGPPCP PCPAPEFLGG PSVFLFPPKP 250 KDTLMISRTP EVTCVVVDVS QEDPEVQFNW YVDGVEVHNA KTKPREEQYN 300 STYRVVSVLT VLHQDWLNGK EYKCKVSNKG LPSSIEKTIS KAKGQPREPQ 350 VYTLPPSQKE MTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV 400 LDSDGSFFLY SKLTVDKSRW QEGNVFSCSV MHEALHNRYT QKSLSLSP 448 Heavy chain anti-F10 QVQLVQSGSE LKKPGASVKV SCKASGYTFT DNNMDWVRQA PGQGLEWMGD50 INTRSGGSIY NEEFQDRVIM TVDKSTDTAY MELSSLRSED TATYHCARRK 100 SYGYYLDEWG EGTLVTVSSA STKGPSVFPL APCSRSTSES TAALGCLVKD 150 YFPEPVTVSW NSGALTSGVH TFPAVLQSSG LYSLSSVVTV PSSSLGTQTY 200 TCNVDHKPSN TKVDKRVESK YGPPCPPCPA PEFLGGPSVF LFPPKPKDTL 250 MISRTPEVTC VVVDVSQEDP EVQFNWYVDG VEVHNAKTKP REEQYNSTYR 300 VVSVLTVLHQ DWLNGKEYKC KVSNKGLPSS IEKTISKAKG QPREPQVYTL 350 PPSQEEMTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD 400 GSFFLYSKLT VDKSRWQEGN VFSCSVMHEA LHNHYTQESL SLSP 444 Light chain DIQMTQSPSS LSASVGDRVT ITCKASRNIE RQLAWYQQKP GQAPELLIYQ 50 ASRKESGVPD RFSGSRYGTD FTLTISSLQP EDIATYYCQQ YSDPPLTFGG 100 GTKVEIKRTV AAPSVFIFPP SDEQLKSGTA SVVCLLNNFY PREAKVQWKV 150 DNALQSGNSQ ESVTEQDSKD STYSLSSTLT LSKADYEKHK VYACEVTHQG 200 LSSPVTKSFN RGEC About drugspider: Drugspider provides, freely, experts verified pipeline/marketed drugs data. The data includes INN/USAN name, brand name, lab code, chemical name, company, clinical trials, ATC codes etc. The intention of drugspider is to help analysts and companies with quickly accessible, trustworthy data of drugs..

Alalevonadifloxacin

INN name:	Alalevonadifloxacin
Lab codes:	WCK-2349
Chemical name:	(5S)-8-[4-(L-alanyloxy)piperidin-1-yl]-9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid
Molecular formula:	C22H26FN3O5
Chemical Structure:
CAS Registry Number:	706809-20-3
Originator:	Wockhardt

Acebilustat

INN name:	Acebilustat
Lab codes:	CTX-4430
Chemical name:	4-{[(1S,4S)-5-({4-[4-(1,3-oxazol-2-yl)phenoxy]phenyl}methyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]methyl}benzoic acid
Molecular formula:	C29H27N3O4
Chemical Structure:
CAS Registry Number:	943764-99-6
Originator:	Celtaxsys